What's it?
We developed a series of rules for transforming protein interactions from pathway to binary model, and the protein interactions from seven pathway databases, including PID, BioCarta, Reactome, NetPath, INOH, SPIKE and KEGG, were transformed based on these rules. These pathway-derived binary protein interactions were integrated with PPIs from other five PPI databases including HPRD, IntAct, BioGRID, MINT and DIP, to develop integrated dataset named PathPPI.
How to use it?
Here provides tab-delimited text files with SIF (simple interaction format) of biological pathway PPI (BiolPPI), technology PPI (TechPPI) and integrated PathPPI respectively. These files can be load into Cytoscape or other software, and be easily processed.
Institute
Fudan University (复旦大学)
Author
Hailin Tang (唐海琳),Fan Zhong (钟凡)
Support
Publication
Resource Download
Funding source
[{"id":"1","name":"CNHPP int'l project 3:2014DFB30020(中国人类蛋白质组学数据的知识发现)"}]