What's it?
Autoantibodies are antibodies that are produced by the B-cell immune system against an individual’s own antigens and play pivotal roles in the maintenance of healthy individuals’ homeostasis, as well as in tumors and autoimmune diseases. In the last two decades, tremendous efforts have been devoted to elucidate the generation, evolution and function of autoantibodies and their targets, autoantigens [1-9]. However, the previously identified autoantigens are randomly dispersed in the literature.
How to use it?
Here we present a database containing 1,126 well-annotated autoantigens, determined by text-mining and manual curation [10]. AAgAtlas database 1.0 provides a user-friendly interface to conveniently browse, retrieve and download the list of autoantigens and their associated diseases. This database is freely accessible at http://biokb.ncpsb.org/aagatlas.
Institute
Beijing Proteome Research Center(BPRC) (北京蛋白质组研究中心)
Author
Dong Li(李栋),Fuchu He (贺福初)
Support
Publication
Figure
Funding source
[{"id":5,"name":"Program of Precision Medicine:2016YFC0901905(精准医学知识库管理与共享平台开发)"}]