What's it?
LncBook is a curated knowledgebase of human lncRNAs that features a comprehensive collection of human lncRNAs and systematic curation of lncRNAs by multi-omics data integration, functional annotation and disease association. The current implementation of LncBook houses a large number of 270,044 lncRNAs and includes 1,867 featured lncRNAs with 3,762 lncRNA-function associations. It also integrates an abundance of multi-omics data from expression, methylation, genome variation and lncRNA-miRNA interaction. In addition, LncBook includes 3,772 experimentally validated lncRNA-disease associations and identifies a total of 97,998 lncRNAs that are putatively disease-associated. To facilitate online analysis, a series of useful tools such as coding potential prediction, sequence search, etc., are deployed in LncBook.
How to use it?
Users can search by different terms in the homepage, such as gene symbol, gene id transcript id, disease name, MeSH Ontology, Functional Mechanism, Biological Process, Classification. Also, it is easy to search specific lncRNA or a specific group of lncRNAs in each resource, e,g,, “Disease”, “Function”, “Expression”, “Methylation”.
Institute
BEIJING INSTITUTE OF GENOMICS (中国科学院北京基因组研究所)
Author
Lina Ma (马利娜)
Support
Publication
Figure
Funding source
[{"id":"Strategic Priority Research Program of the Chinese Academy of Sciences [XDA19050302, XDB13040500]","name":"Strategic Priority Research Program of the Chinese Academy of Sciences [XDA19050302, XDB13040500]"}]